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β-cell-specific CD8 T cell phenotype in type 1 diabetes reflects chronic autoantigen exposure
Autoreactive CD8 T cells play a central role in the destruction of pancreatic islet β-cells that leads to type 1 diabetes, yet the key features of this immune-mediated process remain poorly defined. In this study, we combined high definition polychromatic flow cytometry with ultrasensitive peptide-h...
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| Veröffentlicht in: | Diabetes |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4557541/ https://ncbi.nlm.nih.gov/pubmed/25249579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0332 |
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