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KSHV Latency Locus Cooperates with Myc to Drive Lymphoma in Mice

Kaposi sarcoma-associated herpesvirus (KSHV) has been linked to Kaposi sarcoma and B-cell malignancies. Mechanisms of KSHV-induced oncogenesis remain elusive, however, in part due to lack of reliable in vivo models. Recently, we showed that transgenic mice expressing the KSHV latent genes, including...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Sin, Sang-Hoon, Kim, Yongbaek, Eason, Anthony, Dittmer, Dirk P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556645/
https://ncbi.nlm.nih.gov/pubmed/26327622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005135
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