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Kaposi's Sarcoma-Associated Herpesvirus Latency Locus Compensates for Interleukin-6 in Initial B Cell Activation

Interleukin 6 (IL-6) is considered a proliferation and survival factor for B cells. To assess the role of IL-6 in Kaposi sarcoma-associated herpesvirus (KSHV) latency, KSHV latency locus-transgenic mice (referred to as latency mice) lacking IL-6 were evaluated. IL-6(−/−) latency mice had the same ph...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Sin, Sang-Hoon, Kang, Sun Ah, Kim, Yongbaek, Eason, Anthony, Tan, Kelly, An, Hyowon, Dittmer, Dirk P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734016/
https://ncbi.nlm.nih.gov/pubmed/26656696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02456-15
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