Kaposi's Sarcoma-Associated Herpesvirus Latency Locus Renders B Cells Hyperresponsive to Secondary Infections

Kaposi's sarcoma-associated herpesvirus (KSHV) induces B cell hyperplasia and neoplasia, such as multicentric Castleman's disease (MCD) and primary effusion lymphoma (PEL). To explore KSHV-induced B cell reprogramming in vivo, we expressed the KSHV latency locus, inclusive of all viral mic...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Sin, Sang-Hoon, Eason, Anthony B., Bigi, Rachele, Kim, Yongbaek, Kang, SunAh, Tan, Kelly, Seltzer, Tischan A., Venkataramanan, Raman, An, Hyowon, Dittmer, Dirk P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146794/
https://ncbi.nlm.nih.gov/pubmed/30021906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01138-18
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