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Viral latency locus augments B-cell response in vivo to induce chronic marginal zone enlargement, plasma cell hyperplasia, and lymphoma

Kaposi sarcoma (KS) is associated with KS-associated herpesvirus (KSHV). This virus also causes B-cell lymphoma and B-cell hyperplasia. There exists no in vivo model for KSHV-associated B-cell malignancies or premalignant persistence in B cells. We generated a transgenic mouse that expresses multipl...

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Bibliografiska uppgifter
Huvudupphovsmän: Sin, Sang-Hoon, Dittmer, Dirk P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624941/
https://ncbi.nlm.nih.gov/pubmed/23365457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-03-415620
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