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Structural constraints determine the glycosylation of HIV-1 envelope trimers
A highly glycosylated, trimeric envelope glycoprotein (Env) mediates HIV-1 cell entry. The high density and heterogeneity of the glycans shield Env from recognition by the immune system but, paradoxically, many potent broadly neutralizing antibodies (bNAbs) recognize epitopes involving this glycan s...
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| 出版年: | Cell Rep |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4555872/ https://ncbi.nlm.nih.gov/pubmed/26051934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.05.017 |
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