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Structural constraints determine the glycosylation of HIV-1 envelope trimers
A highly glycosylated, trimeric envelope glycoprotein (Env) mediates HIV-1 cell entry. The high density and heterogeneity of the glycans shield Env from recognition by the immune system but, paradoxically, many potent broadly neutralizing antibodies (bNAbs) recognize epitopes involving this glycan s...
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| Veröffentlicht in: | Cell Rep |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4555872/ https://ncbi.nlm.nih.gov/pubmed/26051934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.05.017 |
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