Structural constraints determine the glycosylation of HIV-1 envelope trimers

A highly glycosylated, trimeric envelope glycoprotein (Env) mediates HIV-1 cell entry. The high density and heterogeneity of the glycans shield Env from recognition by the immune system but, paradoxically, many potent broadly neutralizing antibodies (bNAbs) recognize epitopes involving this glycan s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Rep
Egile Nagusiak: Pritchard, Laura K., Vasiljevic, Snezana, Ozorowski, Gabriel, Seabright, Gemma E., Cupo, Albert, Ringe, Rajesh, Kim, Helen J., Sanders, Rogier W., Doores, Katie J., Burton, Dennis R., Wilson, Ian A., Ward, Andrew B., Moore, John P., Crispin, Max
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555872/
https://ncbi.nlm.nih.gov/pubmed/26051934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.05.017
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