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Structural Modeling Insights into Human VKORC1 Phenotypes
Vitamin K 2,3-epoxide reductase complex subunit 1 (VKORC1) catalyses the reduction of vitamin K and its 2,3-epoxide essential to sustain γ-carboxylation of vitamin K-dependent proteins. Two different phenotypes are associated with mutations in human VKORC1. The majority of mutations cause resistance...
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| Publié dans: | Nutrients |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4555152/ https://ncbi.nlm.nih.gov/pubmed/26287237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu7085313 |
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