VKORC1-dependent pharmacokinetics of intravenous and oral phylloquinone (vitamin K1) mixed micelles formulation

OBJECTIVE: The pharmacokinetics of phylloquinone (vitamin K1) were evaluated in healthy human adult volunteers (15 male and 15 female) following oral and intravenous administration of a mixed micelles formulation (Konakion® MM 2 mg) in an open label study design. The subjects were allocated to one o...

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Detaylı Bibliyografya
Asıl Yazarlar: Marinova, Milka, Lütjohann, Dieter, Breuer, Olof, Kölsch, Heike, Westhofen, Philipp, Watzka, Matthias, Mengel, Martin, Stoffel-Wagner, Birgit, Hartmann, Gunther, Coch, Christoph, Oldenburg, Johannes
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer-Verlag 2012
Konular:
Pharmacokinetics and Disposition
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572390/
https://ncbi.nlm.nih.gov/pubmed/22864379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-012-1362-y
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