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Identifying the genotype behind the phenotype: a role model found in VKORC1 and its association with warfarin dosing

Genotype-phenotype studies in pharmacogenomics promise to identify the genetic factors that contribute substantially to variation in individual drug response. While most genetic association studies have failed to deliver the promise, several recent examples serve as a reminder that these association...

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Detalles Bibliográficos
Main Authors: Crawford, Dana C., Ritchie, Marylyn D., Rieder, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112050/
https://ncbi.nlm.nih.gov/pubmed/17465713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/14622416.8.5.487
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