VKORC1 polymorphisms, haplotypes and haplotype groups on warfarin dose among African–Americans and European–Americans

BACKGROUND: Although the influence of VKORC1 and CYP2C9 polymorphisms on warfarin response has been studied, variability in dose explained by CYP2C9 and VKORC1 is lower among African–Americans compared with European–Americans. This has lead investigators to hypothesize that assessment of VKORC1 hapl...

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Main Authors: Limdi, Nita A, Beasley, T Mark, Crowley, Michael R, Goldstein, Joyce A, Rieder, Mark J, Flockhart, David A, Arnett, Donna K, Acton, Ronald T, Liu, Nianjun
格式: Artigo
語言:Inglês
出版: 2008
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586955/
https://ncbi.nlm.nih.gov/pubmed/18855533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/14622416.9.10.1445
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