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Influence of CYP2C9 and VKORC1 on warfarin dose, anticoagulation attainment and maintenance among European American and African Americans

AIMS: The influence of CYP2C9 and VKORC1 on warfarin dose, time to target INR, time to stabilization, and risk of over-anticoagulation (INR>4) was assessed after adjustment for clinical factors, intra-individual variation in environmental factors and unobserved heterogeneity. MATERIALS AND METHOD...

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Detalhes bibliográficos
Main Authors: Limdi, NA, Arnett, DK, Goldstein, JA, Beasley, TM, McGwin, G, Adler, BK, Acton, RT
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757655/
https://ncbi.nlm.nih.gov/pubmed/18466099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/14622416.9.5.511
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