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VKORC1 polymorphisms, haplotypes and haplotype groups on warfarin dose among African–Americans and European–Americans

BACKGROUND: Although the influence of VKORC1 and CYP2C9 polymorphisms on warfarin response has been studied, variability in dose explained by CYP2C9 and VKORC1 is lower among African–Americans compared with European–Americans. This has lead investigators to hypothesize that assessment of VKORC1 hapl...

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Autors principals: Limdi, Nita A, Beasley, T Mark, Crowley, Michael R, Goldstein, Joyce A, Rieder, Mark J, Flockhart, David A, Arnett, Donna K, Acton, Ronald T, Liu, Nianjun
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586955/
https://ncbi.nlm.nih.gov/pubmed/18855533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/14622416.9.10.1445
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