A carregar...

Irreversible binding of an anticancer compound (BI-94) to plasma proteins

1. We investigated the mechanisms responsible for the in vivo instability of a benzofurazan compound BI-94 (NSC228148) with potent anti-cancer activity. 2. BI-94 was stable in MeOH, water, and in various buffers at pHs 2.5–5, regardless of the buffer composition. In contrast, BI-94 was unstable in N...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Xenobiotica
Main Authors: Gautam, Nagsen, Thakare, Rhishikesh, Rana, Sandeep, Natarajan, Amarnath, Alnouti, Yazen
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553108/
https://ncbi.nlm.nih.gov/pubmed/25869245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00498254.2015.1025250
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!