Pharmacokinetics, Biodistribution, and Toxicity of Folic Acid-Coated Antiretroviral Nanoformulations

The drug delivery platform for folic acid (FA)-coated nanoformulated ritonavir (RTV)-boosted atazanavir (FA-nanoATV/r) using poloxamer 407 was developed to enhance cell and tissue targeting for a range of antiretroviral drugs. Such formulations would serve to extend the drug half-life while improvin...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Gautam, Nagsen, Puligujja, Pavan, Balkundi, Shantanu, Thakare, Rhishikesh, Liu, Xin-Ming, Fox, Howard S., McMillan, JoEllyn, Gendelman, Howard E., Alnouti, Yazen
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249580/
https://ncbi.nlm.nih.gov/pubmed/25288084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04108-14
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