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Irreversible binding of zomepirac to plasma protein in vitro and in vivo.

Zomepirac is a nonsteroidal anti-inflammatory drug recently withdrawn from use because of an unexplained high incidence of immunological reactions. It is metabolized in humans to a reactive, unstable acyl glucuronide which accumulates in plasma. Because of the similarity of zomepirac glucuronide to...

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Autors principals: Smith, P C, McDonagh, A F, Benet, L Z
Format: Artigo
Idioma:Inglês
Publicat: 1986
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC423485/
https://ncbi.nlm.nih.gov/pubmed/3949982
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