Mechanisms of the Androgen Receptor Splicing in Prostate Cancer Cells

Prostate tumors develop resistance to androgen deprivation therapy (ADT) by multiple mechanisms, one of which is to express constitutively active androgen receptor (AR) splice variants lacking the ligand binding domain. AR splice variant 7 (AR-V7, also termed AR3) is the most abundantly expressed va...

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Bibliographische Detailangaben
Veröffentlicht in:Oncogene
Hauptverfasser: Liu, Liang liang, Xie, Ning, Sun, Shihua, Plymate, Stephen, Mostaghel, Elahe, Dong, Xuesen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553036/
https://ncbi.nlm.nih.gov/pubmed/23851510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.284
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