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Targeted Knockdown of Hepatic SOAT2 with Antisense Oligonucleotides Stabilizes Atherosclerotic Plaque in ApoB100-only LDLr(−/−) Mice
OBJECTIVE: To test the hypothesis that the attenuation of CO packaging into apoB-containing lipoproteins will arrest progression of pre-existing atherosclerotic lesions. APPROACH AND RESULTS: Atherosclerosis was induced in apoB-100 only, LDLr(−/−) mice by feeding a diet enriched in cis-monounsaturat...
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| Publicado no: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4552612/ https://ncbi.nlm.nih.gov/pubmed/26229140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.305747 |
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