In vivo inhibition of nuclear factor of activated T-cells leads to atherosclerotic plaque regression in IGF-II/LDLR(–/–)ApoB(100/100) mice

AIMS: Despite vast clinical experience linking diabetes and atherosclerosis, the molecular mechanisms leading to accelerated vascular damage are still unclear. Here, we investigated the effects of nuclear factor of activated T-cells inhibition on plaque burden in a novel mouse model of type 2 diabet...

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Detalhes bibliográficos
Publicado no:Diab Vasc Dis Res
Main Authors: Blanco, Fabiana, Heinonen, Suvi E, Gurzeler, Erika, Berglund, Lisa M, Dutius Andersson, Anna-Maria, Kotova, Olga, Jönsson-Rylander, Ann-Cathrine, Ylä-Herttuala, Seppo, Gomez, Maria F
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039864/
https://ncbi.nlm.nih.gov/pubmed/29499628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1479164118759220
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