Cloning of ApoB Intrabodies: Specific Knockdown of ApoB in HepG2 Cells

Apolipoprotein (apo) B is essential for the assembly and secretion of triglyceride-rich lipoproteins made by the liver. As the sole protein component in LDL, apoB is an important determinant of atherosclerosis susceptibility and a potential pharmaceutical target. Single-chain antibodies (sFvs) are t...

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Bibliographic Details
Main Authors: Liao, Wei, Strube, Randall W., Milne, Ross W., Chen, Si-Yi, Chan, Lawrence
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2496960/
https://ncbi.nlm.nih.gov/pubmed/18558087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.06.020
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