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Ubiquitination regulates the assembly of VLDL in HepG2 cells and is the committing step of the apoB-100 ERAD pathway

Apolipoprotein B-100 (apoB-100) is degraded by endoplasmic reticulum-associated degradation (ERAD) when lipid availability limits assembly of VLDLs. The ubiquitin ligase gp78 and the AAA-ATPase p97 have been implicated in the proteasomal degradation of apoB-100. To study the relationship between ERA...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fisher, Eric A., Khanna, Neeraj A., McLeod, Roger S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Biochemistry and Molecular Biology 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090238/
https://ncbi.nlm.nih.gov/pubmed/21421992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M011726
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