Intramolecular C2 Domain-Mediated Autoinhibition of Protein Kinase C βII

The signaling output of protein kinase C (PKC) is exquisitely controlled, with its disruption resulting in pathophysiologies. Identifying the structural basis for autoinhibition is central to developing effective therapies for cancer, where PKC activity needs to be enhanced, or neurodegenerative dis...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Rep
Egile Nagusiak: Antal, Corina E., Callender, Julia A., Kornev, Alexandr P., Taylor, Susan S., Newton, Alexandra C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551583/
https://ncbi.nlm.nih.gov/pubmed/26279568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.07.039
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