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The Amino Acid Specificity for Activation of Phenylalanine Hydroxylase Matches the Specificity for Stabilization of Regulatory Domain Dimers

[Image: see text] Liver phenylalanine hydroxylase is allosterically activated by phenylalanine. The structural changes that accompany activation have not been identified, but recent studies of the effects of phenylalanine on the isolated regulatory domain of the enzyme support a model in which pheny...

詳細記述

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書誌詳細
出版年:Biochemistry
主要な著者: Zhang, Shengnan, Hinck, Andrew P., Fitzpatrick, Paul F.
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2015
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551101/
https://ncbi.nlm.nih.gov/pubmed/26252467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00616
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