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Pharmacological inhibition of DNA-PK stimulates Cas9-mediated genome editing
BACKGROUND: The ability to modify the genome of any cell at a precise location has drastically improved with the recent discovery and implementation of CRISPR/Cas9 editing technology. However, the capacity to introduce specific directed changes at given loci is hampered by the fact that the major ce...
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| Publicado no: | Genome Med |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4550049/ https://ncbi.nlm.nih.gov/pubmed/26307031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0215-6 |
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