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Versatile and robust genome editing with Streptococcus thermophilus CRISPR1-Cas9
Targeting definite genomic locations using CRISPR-Cas systems requires a set of enzymes with unique protospacer adjacent motif (PAM) compatibilities. To expand this repertoire, we engineered nucleases, cytosine base editors, and adenine base editors from the archetypal Streptococcus thermophilus CRI...
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| Publicado no: | Genome Res |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6961573/ https://ncbi.nlm.nih.gov/pubmed/31900288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.255414.119 |
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