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Somatic mutation of immunoglobulin lambda chains: a segment of the major intron hypermutates as much as the complementarity-determining regions.

The rate and nature of hypermutation of immunoglobulin genes are of prime importance in the affinity maturation of antibodies. Although a considerable body of information has been gathered for kappa light chains, there is much less data for lambda chains. We have derived a large data base of somatic...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: González-Fernández, A, Gupta, S K, Pannell, R, Neuberger, M S, Milstein, C
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1994
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC45489/
https://ncbi.nlm.nih.gov/pubmed/7809087
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