טוען...

Somatic hypermutation of immunoglobulin kappa may depend on sequences 3' of C kappa and occurs on passenger transgenes.

We have compared the pattern of somatic mutation in different immunoglobulin kappa transgenes and suggest that an element(s) located between 1 kb and 9 kb 3' of C kappa is necessary for somatic hypermutation of the antibody V gene. The sequences of transgenic and endogenous Ig V regions were de...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Sharpe, M J, Milstein, C, Jarvis, J M, Neuberger, M S
פורמט: Artigo
שפה:Inglês
יצא לאור: 1991
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC452901/
https://ncbi.nlm.nih.gov/pubmed/1905999
תגים: הוספת תג
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