HLA Class-II Associated HIV Polymorphisms Predict Escape from CD4+ T Cell Responses

Antiretroviral therapy, antibody and CD8(+) T cell-mediated responses targeting human immunodeficiency virus-1 (HIV-1) exert selection pressure on the virus necessitating escape; however, the ability of CD4(+) T cells to exert selective pressure remains unclear. Using a computational approach on HIV...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Pathog
Main Authors: Erdmann, Nathan, Du, Victor Y., Carlson, Jonathan, Schaefer, Malinda, Jureka, Alexander, Sterrett, Sarah, Yue, Ling, Dilernia, Dario, Lakhi, Shabir, Tang, Jianming, Sidney, John, Gilmour, Jill, Allen, Susan, Hunter, Eric, Heath, Sonya, Bansal, Anju, Goepfert, Paul A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547780/
https://ncbi.nlm.nih.gov/pubmed/26302050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005111
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