HLA Class-II Associated HIV Polymorphisms Predict Escape from CD4+ T Cell Responses

Antiretroviral therapy, antibody and CD8(+) T cell-mediated responses targeting human immunodeficiency virus-1 (HIV-1) exert selection pressure on the virus necessitating escape; however, the ability of CD4(+) T cells to exert selective pressure remains unclear. Using a computational approach on HIV...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Erdmann, Nathan, Du, Victor Y., Carlson, Jonathan, Schaefer, Malinda, Jureka, Alexander, Sterrett, Sarah, Yue, Ling, Dilernia, Dario, Lakhi, Shabir, Tang, Jianming, Sidney, John, Gilmour, Jill, Allen, Susan, Hunter, Eric, Heath, Sonya, Bansal, Anju, Goepfert, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547780/
https://ncbi.nlm.nih.gov/pubmed/26302050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005111
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