Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703–positive individuals and their transmission recipients

HLA-B*57 is the class I allele most consistently associated with control of human immunodeficiency virus (HIV) replication, which may be linked to the specific HIV peptides that this allele presents to cytotoxic T lymphocytes (CTLs), and the resulting efficacy of these cellular immune responses. In...

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Autors principals: Crawford, Hayley, Lumm, Wendy, Leslie, Alasdair, Schaefer, Malinda, Boeras, Debrah, Prado, Julia G., Tang, Jianming, Farmer, Paul, Ndung'u, Thumbi, Lakhi, Shabir, Gilmour, Jill, Goepfert, Paul, Walker, Bruce D., Kaslow, Richard, Mulenga, Joseph, Allen, Susan, Goulder, Philip J.R., Hunter, Eric
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715113/
https://ncbi.nlm.nih.gov/pubmed/19307327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081984
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