Upregulation of microRNA-122 by farnesoid X receptor suppresses the growth of hepatocellular carcinoma cells

BACKGROUND: microRNA-122 (miR-122) is the most abundant and specific miRNA in the liver. It acts as an important tumor suppressor in hepatocellular carcinoma (HCC) through regulating its target genes, but details of its own regulation are largely unknown. Farnesoid X receptor (FXR), a transcription...

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Gepubliceerd in:Mol Cancer
Hoofdauteurs: He, Jialin, Zhao, Kai, Zheng, Lu, Xu, Zhizhen, Gong, Wei, Chen, Shan, Shen, Xiaodong, Huang, Gang, Gao, Min, Zeng, Yijun, Zhang, Yan, He, Fengtian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547435/
https://ncbi.nlm.nih.gov/pubmed/26302777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0427-9
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