FXR induces SOCS3 and suppresses hepatocellular carcinoma

Suppressor of cytokine signaling 3 (SOCS3) is regarded as a vital repressor in the liver carcinogenesis mainly by inhibiting signal transducer and activator of transcription 3 (STAT3) activity. Farnesoid X Receptor (FXR), highly expressed in liver, has an important role in protecting against hepatoc...

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Udgivet i:Oncotarget
Main Authors: Guo, Fei, Xu, Zhizhen, Zhang, Yan, Jiang, Peng, Huang, Gang, Chen, Shan, Lyu, Xilin, Zheng, Ping, Zhao, Xin, Zeng, Yijun, Wang, Shuguang, He, Fengtian
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741476/
https://ncbi.nlm.nih.gov/pubmed/26416445
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