Upregulation of microRNA-122 by farnesoid X receptor suppresses the growth of hepatocellular carcinoma cells

BACKGROUND: microRNA-122 (miR-122) is the most abundant and specific miRNA in the liver. It acts as an important tumor suppressor in hepatocellular carcinoma (HCC) through regulating its target genes, but details of its own regulation are largely unknown. Farnesoid X receptor (FXR), a transcription...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: He, Jialin, Zhao, Kai, Zheng, Lu, Xu, Zhizhen, Gong, Wei, Chen, Shan, Shen, Xiaodong, Huang, Gang, Gao, Min, Zeng, Yijun, Zhang, Yan, He, Fengtian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547435/
https://ncbi.nlm.nih.gov/pubmed/26302777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0427-9
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