Upregulation of microRNA-122 by farnesoid X receptor suppresses the growth of hepatocellular carcinoma cells

BACKGROUND: microRNA-122 (miR-122) is the most abundant and specific miRNA in the liver. It acts as an important tumor suppressor in hepatocellular carcinoma (HCC) through regulating its target genes, but details of its own regulation are largely unknown. Farnesoid X receptor (FXR), a transcription...

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Bibliografiske detaljer
Udgivet i:Mol Cancer
Main Authors: He, Jialin, Zhao, Kai, Zheng, Lu, Xu, Zhizhen, Gong, Wei, Chen, Shan, Shen, Xiaodong, Huang, Gang, Gao, Min, Zeng, Yijun, Zhang, Yan, He, Fengtian
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547435/
https://ncbi.nlm.nih.gov/pubmed/26302777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0427-9
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