Upregulation of microRNA-122 by farnesoid X receptor suppresses the growth of hepatocellular carcinoma cells

BACKGROUND: microRNA-122 (miR-122) is the most abundant and specific miRNA in the liver. It acts as an important tumor suppressor in hepatocellular carcinoma (HCC) through regulating its target genes, but details of its own regulation are largely unknown. Farnesoid X receptor (FXR), a transcription...

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Vydáno v:Mol Cancer
Hlavní autoři: He, Jialin, Zhao, Kai, Zheng, Lu, Xu, Zhizhen, Gong, Wei, Chen, Shan, Shen, Xiaodong, Huang, Gang, Gao, Min, Zeng, Yijun, Zhang, Yan, He, Fengtian
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547435/
https://ncbi.nlm.nih.gov/pubmed/26302777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0427-9
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