MicroRNA-122 Triggers Mesenchymal-Epithelial Transition and Suppresses Hepatocellular Carcinoma Cell Motility and Invasion by Targeting RhoA

The loss of microRNA-122 (miR-122) expression is strongly associated with increased invasion and metastasis, and poor prognosis of hepatocellular carcinoma (HCC), however, the underlying mechanisms remain poorly understood. In the present study, we observed that miR-122 over-expression in HCC cell l...

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主要な著者: Wang, Sheng-Chun, Lin, Xiao-Lin, Li, Jing, Zhang, Ting-Ting, Wang, Hui-Yan, Shi, Jun-Wen, Yang, Sheng, Zhao, Wen-Tao, Xie, Rao-Ying, Wei, Fang, Qin, Yu-Juan, Chen, Lin, Yang, Jie, Yao, Kai-Tai, Xiao, Dong
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081555/
https://ncbi.nlm.nih.gov/pubmed/24992599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101330
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