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RHPN2 Drives Mesenchymal Transformation in Malignant Glioma by Triggering RhoA Activation
Mesenchymal (MES) transformation is a hallmark of aggressive glioblastoma (GBM). Here we report the development of an unbiased method for computational integration of copy number variation, expression and mutation data from large datasets. Using this method we identified RHPN2 as a central genetic d...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3805507/ https://ncbi.nlm.nih.gov/pubmed/23774217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1168-T |
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