Exon 9 skipping of apoptotic caspase-2 pre-mRNA is promoted by SRp20 through interaction with exon 8

Alternative splicing plays an important role in gene expression by producing different proteins from a gene. Caspase-2 pre-mRNA produces anti-apoptotic Casp-2S and proapoptotic Casp-2L proteins through exon 9 inclusion or skipping. However, the molecular mechanisms of exon 9 splicing are not well un...

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Bibliografske podrobnosti
izdano v:Biochim Biophys Acta
Main Authors: Jang, Ha Na, Lee, Minho, Loh, Tiing Jen, Choi, Seung-Woo, Oh, Hyun Kyung, Moon, Heegyum, Cho, Sunghee, Hong, Seong-Eui, Kim, Do Han, Sheng, Zhi, Green, Michael R, Park, Daeho, Zheng, Xuexiu, Shen, Haihong
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547346/
https://ncbi.nlm.nih.gov/pubmed/24321384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2013.11.006
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