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Dynamic localization of Mps1 kinase to kinetochores is essential for accurate spindle microtubule attachment
The spindle assembly checkpoint (SAC) is a conserved signaling pathway that monitors faithful chromosome segregation during mitosis. As a core component of SAC, the evolutionarily conserved kinase monopolar spindle 1 (Mps1) has been implicated in regulating chromosome alignment, but the underlying m...
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Published in: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , , , , , |
Format: | Artigo |
Language: | Inglês |
Published: |
National Academy of Sciences
2015
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4547264/ https://ncbi.nlm.nih.gov/pubmed/26240331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508791112 |
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