Dynamic localization of Mps1 kinase to kinetochores is essential for accurate spindle microtubule attachment

The spindle assembly checkpoint (SAC) is a conserved signaling pathway that monitors faithful chromosome segregation during mitosis. As a core component of SAC, the evolutionarily conserved kinase monopolar spindle 1 (Mps1) has been implicated in regulating chromosome alignment, but the underlying m...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Dou, Zhen, Liu, Xing, Wang, Wenwen, Zhu, Tongge, Wang, Xinghui, Xu, Leilei, Abrieu, Ariane, Fu, Chuanhai, Hill, Donald L., Yao, Xuebiao
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2015
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547264/
https://ncbi.nlm.nih.gov/pubmed/26240331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508791112
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