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Increased Aurora B activity causes continuous disruption of kinetochore–microtubule attachments and spindle instability

Aurora B kinase regulates the proper biorientation of sister chromatids during mitosis. Lack of Aurora B kinase function results in the inability to correct erroneous kinetochore–microtubule attachments and gives rise to aneuploidy. Interestingly, increased Aurora B activity also leads to problems w...

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Hlavní autoři: Muñoz-Barrera, Marta, Monje-Casas, Fernando
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183290/
https://ncbi.nlm.nih.gov/pubmed/25201961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1408017111
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