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Correcting aberrant kinetochore microtubule attachments: a hidden regulation of Aurora B on microtubules

For equal chromosome segregation, a pair of kinetochores on each duplicated chromosome must attach to microtubules connecting to opposite poles. The protein kinase Aurora B plays a critical role in destabilizing microtubules attached in a wrong orientation through phosphorylating kinetochore protein...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Curr Opin Cell Biol
Glavni avtor: Funabiki, Hironori
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6646109/
https://ncbi.nlm.nih.gov/pubmed/30684807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2018.12.007
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