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Increased Aurora B activity causes continuous disruption of kinetochore–microtubule attachments and spindle instability
Aurora B kinase regulates the proper biorientation of sister chromatids during mitosis. Lack of Aurora B kinase function results in the inability to correct erroneous kinetochore–microtubule attachments and gives rise to aneuploidy. Interestingly, increased Aurora B activity also leads to problems w...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , |
|---|---|
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
National Academy of Sciences
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4183290/ https://ncbi.nlm.nih.gov/pubmed/25201961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1408017111 |
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