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Increased Aurora B activity causes continuous disruption of kinetochore–microtubule attachments and spindle instability
Aurora B kinase regulates the proper biorientation of sister chromatids during mitosis. Lack of Aurora B kinase function results in the inability to correct erroneous kinetochore–microtubule attachments and gives rise to aneuploidy. Interestingly, increased Aurora B activity also leads to problems w...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4183290/ https://ncbi.nlm.nih.gov/pubmed/25201961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1408017111 |
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