Loading...
Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules
The overexpression of Aurora kinases in multiple tumors makes these kinases appealing targets for the development of anticancer therapies. This study identified two small molecules with a furanopyrimidine core, IBPR001 and IBPR002, that target Aurora kinases and induce a DFG conformation change at t...
Na minha lista:
| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2013
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3651446/ https://ncbi.nlm.nih.gov/pubmed/23610398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220523110 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|