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Phosphorylation of Microtubule-binding Protein Hec1 by Mitotic Kinase Aurora B Specifies Spindle Checkpoint Kinase Mps1 Signaling at the Kinetochore
The spindle assembly checkpoint (SAC) is a quality control device to ensure accurate chromosome attachment to spindle microtubule for equal segregation of sister chromatid. Aurora B is essential for SAC function by sensing chromosome bi-orientation via spatial regulation of kinetochore substrates. H...
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Prif Awduron: | , , , , , , , , , , , , , , , |
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Fformat: | Artigo |
Iaith: | Inglês |
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American Society for Biochemistry and Molecular Biology
2013
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3861662/ https://ncbi.nlm.nih.gov/pubmed/24187132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.507970 |
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