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Aurora A kinase phosphorylates Hec1 to regulate metaphase kinetochore–microtubule dynamics
Precise regulation of kinetochore–microtubule attachments is essential for successful chromosome segregation. Central to this regulation is Aurora B kinase, which phosphorylates kinetochore substrates to promote microtubule turnover. A critical target of Aurora B is the N-terminal “tail” domain of H...
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| Veröffentlicht in: | J Cell Biol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5748988/ https://ncbi.nlm.nih.gov/pubmed/29187526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201707160 |
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