Dynamic acetylation of the kinetochore-associated protein HEC1 ensures accurate microtubule–kinetochore attachment

Faithful chromosome segregation during mitosis is critical for maintaining genome integrity in cell progeny and relies on accurate and robust kinetochore–microtubule attachments. The NDC80 complex, a tetramer comprising kinetochore protein HEC1 (HEC1), NDC80 kinetochore complex component NUF2 (NUF2)...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Zhao, Gangyin, Cheng, Yubao, Gui, Ping, Cui, Meiying, Liu, Wei, Wang, Wenwen, Wang, Xueying, Ali, Mahboob, Dou, Zhen, Niu, Liwen, Liu, Haiyan, Anderson, Leonard, Ruan, Ke, Hong, Jingjun, Yao, Xuebiao
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2019
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333894/
https://ncbi.nlm.nih.gov/pubmed/30409912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003844
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