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Kinetochore-microtubule attachment relies on the disordered N-terminal tail domain of Hec1

Accurate chromosome segregation is dependent upon kinetochores stably attaching chromosomes to spindle microtubules during mitosis. A long-standing question is how kinetochores are able to maintain stable attachment to the plus-ends of dynamic microtubules that are continually growing and shrinking....

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Bibliografische gegevens
Hoofdauteurs: Guimaraes, Geoffrey J., Dong, Yimin, McEwen, Bruce F., DeLuca, Jennifer G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753282/
https://ncbi.nlm.nih.gov/pubmed/19026543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.08.012
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