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Enhanced aromatic sequons increase oligosaccharyltransferase glycosylation efficiency and glycan homogeneity
N-glycosylation plays an important role in protein folding and function. Previous studies demonstrate that a phenylalanine residue introduced at the n-2 position relative to an Asn-Xxx-Thr/Ser N-glycosylation sequon increases the sequon’s glycan occupancy in insect cells. Here, we show that any arom...
में बचाया:
में प्रकाशित: | Chem Biol |
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मुख्य लेखकों: | , , , , , , , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
2015
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4546532/ https://ncbi.nlm.nih.gov/pubmed/26190824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.06.017 |
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