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P-Glycoprotein Induction Ameliorates Colistin Induced Nephrotoxicity in Cultured Human Proximal Tubular Cells

The pathogenesis of colistin induced nephrotoxicity is poorly understood. Currently there are no effective therapeutic or prophylactic agents available. This study was aimed to determine the mechanism of colistin induced nephrotoxicity and to determine whether P-glycoprotein (P-gp) induction could p...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Lee, Sun-hyo, Kim, Jin-sun, Ravichandran, Kameswaran, Gil, Hyo-Wook, Song, Ho-yeon, Hong, Sae-yong
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545883/
https://ncbi.nlm.nih.gov/pubmed/26287374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136075
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