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Role of Shear Stress on Renal Proximal Tubular Cells for Nephrotoxicity Assays

Drug-induced nephrotoxicity causes huge morbidity and mortality at massive financial cost. The greatest burden of drug-induced acute kidney injury falls on the proximal tubular cells. To maintain their structure and function, renal proximal tubular cells need the shear stress from tubular fluid flow...

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Detalhes bibliográficos
Publicado no:J Toxicol
Main Authors: Birdsall, Holly H., Hammond, Timothy G.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8084667/
https://ncbi.nlm.nih.gov/pubmed/33976696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6643324
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